Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL

Catalog number BNUM3608-50

Price for BNUM3608-50

Size / count 1x 50 µL

About this product

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM3608-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: C-type lectin domain family 4 member K; CD207; CLEC4K; Langerhans cell specific c type lectin; Langerin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD207
Gene ID: 50489
NCBI Gene ID: 199731
UniProt: Q9UJ71
Swiss Prot: Q9UJ71
Host: Mouse
Species Reactivity: Human
Reactivity: CD207|Langerin
Immunogen: Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
Target Antigen: CD207 | Langerin
Clonality: Recombinant Monoclonal
Clone: RLGRN/1821
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa or A549 cells (WB).
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 48 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL?

The catalog number for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL is BNUM3608-50.

What sizes are available for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL in stock?

Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL?

Estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL?

The safety data sheet for Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100724/msds/bnum3608-50.pdf.

What is Langerin / CD207 (Marker of Langerhans Cells) (rLGRN/1821), 1mg/mL used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.