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Product details
Catalog number BNC403646-500
Price for BNC403646-500
Size / count 1x 500 µL
Recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e. g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF640R conjugate, 0.1mg/mL is BNC403646-500.
MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02af061270361e108ec1/msds/bnc403646-500.pdf.
Recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.
Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.
