MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL

Catalog number BNC683646-500

Price for BNC683646-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e. g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC683646-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BDMF; DMSFH; DMSMFH; Epididymis luminal protein 249; HEL249; LGMBF; MeSAdo phosphorylase; Methylthioadenosine phosphorylase; MSAP; MTA phosphorylase; MTAPase; S-methyl-5''-thioadenosine phosphorylase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MTAP
Gene ID: 4507
NCBI Gene ID: 193268
UniProt: Q13126
Swiss Prot: Q13126
Host: Mouse
Species Reactivity: Human
Reactivity: MTAP
Immunogen: Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary)
Target Antigen: MTAP
Clonality: Recombinant Monoclonal
Clone: RMTAP/1813
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HepG2, A431, HeLa or MCF-7 cells. Human kidney tissues (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 31 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL?

The catalog number for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL is BNC683646-500.

What sizes are available for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL in stock?

MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL?

The safety data sheet for MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e109c1e/msds/bnc683646-500.pdf.

What is MTAP (Tumor Suppressor Marker) (rMTAP/1813), CF568 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.