Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL

Catalog number BNC683647-500

Price for BNC683647-500

Size / count 1x 500 µL

About this product

Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin) and spectrin I (also designated fodrin) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC683647-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Beta III spectrin; SCA5; Spectrin beta chain brain 2; Spectrin beta non-erythrocytic 2; Spectrin non-erythroid beta chain 2; Spinocerebellar ataxia 5; SPTBN2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SPTBN2
Gene ID: 6712
NCBI Gene ID: 26915
UniProt: O15020
Swiss Prot: O15020
Host: Mouse
Species Reactivity: Human
Reactivity: Spectrin Beta-III
Immunogen: Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary)
Target Antigen: Spectrin Beta-III
Clonality: Recombinant Monoclonal
Clone: RSPTBN2/1778
Type: Primary
Source: Animal
Origin: Animal
Applications: WB (verified)
Positive Control: PANC-1, HeLa, PC-3 cells. Human brain, pancreas or liver tissues (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 246 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL?

The catalog number for Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL is BNC683647-500.

What sizes are available for Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL?

Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL in stock?

Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL?

Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b5061270361e10af77/msds/bnc683647-500.pdf.

What is Spectrin beta III (SPTBN2) (rSPTBN2/1778), CF568 conjugate, 0.1mg/mL used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.