SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL

Catalog number BNUM3648-50

Price for BNUM3648-50

Size / count 1x 50 µL

About this product

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM3648-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ANOP3; Delta EF2a; MCOPS3 (Microphthalmia Syndromic type 3) ; SOX-2; SRY (sex determining region Y) box 2; SRY related HMG box 2; Transcription factor SOX-2; ysb
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SOX2
Gene ID: 6657
NCBI Gene ID: 518438
UniProt: P48431
Swiss Prot: P48431
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: SOX2
Immunogen: Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
Target Antigen: SOX2
Clonality: Recombinant Monoclonal
Clone: RSOX2/1791
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A549, NCCIT cells. Human lung or cervical carcinoma.
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 34 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL?

The catalog number for SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL is BNUM3648-50.

What sizes are available for SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL?

SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL is available in the following size(s): 1x 50 µL.

Is SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL in stock?

SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL?

SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL?

Estimated delivery time for SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL?

The safety data sheet for SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100b6e/msds/bnum3648-50.pdf.

What is SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), 1mg/mL used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.