PAX5 / BSAP (Early B-Cell Marker) (PAX5/3735), CF405S conjugate, 0.1mg/mL

About this product

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 21, 000, full-length human proteins. The PAX5 gene is a member of thepaired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC043735-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

B cell lineage specific activator; BSAP; EBB-1; KLP; Paired box 5

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

PAX5

Gene ID

5079

NCBI Gene ID

654464

UniProt

Q02548

Swiss Prot

Q02548

Host

Mouse

Species Reactivity

Human

Reactivity

BSAP|PAX5

Immunogen

A recombinant fragment (around aa 235-382) of human PAX5 protein (exact sequence is proprietary)

Target Antigen

BSAP | PAX5

Clonality

Monoclonal

Clone

PAX5/3735

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified) |WB (verified)

Positive Control

DAUDI or Ramos Cells. Tonsil, spleen, Lymph Node or Colon Carcinoma.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

42 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF405S