AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL

Catalog number BNC043786-100

Price for BNC043786-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 62 kDa, which is identified as AKT1. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKBbeta or RacPK-beta) and Akt3 (also designated PKB-gamma or thymoma viral proto-oncogene 3), which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. All members of the Akt family have a Pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-beta tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase (s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC043786-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AKT1; PKB; Protein Kinase B Alpha; RAC-alpha serine/threonine-protein kinase
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: AKT1
Gene ID: 207
NCBI Gene ID: 525622
UniProt: P31749
Swiss Prot: P31749
Host: Mouse
Species Reactivity: Human
Reactivity: AKT1
Immunogen: Recombinant fragment of human AKT1 protein (around aa 85-189) (exact sequence is proprietary)
Target Antigen: AKT1
Clonality: Recombinant Monoclonal
Clone: RAKT1/2491
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: PDGF-treated NIH/3T3 cells. HeLa cell lysates. Human pancreas or cervical carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 62 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL?

The catalog number for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL is BNC043786-100.

What sizes are available for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL?

AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL in stock?

AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL?

AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL?

The safety data sheet for AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a2061270361e1047c4/msds/bnc043786-100.pdf.

What is AKT1 (Prognostic Marker for Neuroendocrine Tumors) (rAKT1/2491), CF405S conjugate, 0.1mg/mL used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.