SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL

Catalog number BNC473811-500

Price for BNC473811-500

Size / count 1x 500 µL

About this product

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC473811-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ANOP3; Delta EF2a; MCOPS3 (Microphthalmia Syndromic type 3) ; SOX-2; SRY (sex determining region Y) box 2; SRY related HMG box 2; Transcription factor SOX-2; ysb
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SOX2
Gene ID: 6657
NCBI Gene ID: 518438
UniProt: P48431
Swiss Prot: P48431
Host: Rabbit
Species Reactivity: Human, Mouse
Reactivity: SOX2
Immunogen: Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
Target Antigen: SOX2
Clonality: Recombinant Monoclonal
Clone: SOX2/3811R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: MCF-7 cells. Lung or Cervical carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 34 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL?

The catalog number for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL is BNC473811-500.

What sizes are available for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL?

SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL in stock?

SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL?

SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100478/msds/bnc473811-500.pdf.

What is SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), CF647 conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.