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Product details

SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB3811-500

Price for BNCB3811-500

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Size / count 1x 500 µL

About this product

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB3811-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ANOP3; Delta EF2a; MCOPS3 (Microphthalmia Syndromic type 3) ; SOX-2; SRY (sex determining region Y) box 2; SRY related HMG box 2; Transcription factor SOX-2; ysb
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SOX2
Gene ID
6657
NCBI Gene ID
518438
UniProt
P48431
Swiss Prot
P48431
Host
Rabbit
Species Reactivity
Human, Mouse
Reactivity
SOX2
Immunogen
Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
Target Antigen
SOX2
Clonality
Recombinant Monoclonal
Clone
SOX2/3811R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
MCF-7 cells. Lung or Cervical carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
34 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL?

The catalog number for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL is BNCB3811-500.

What sizes are available for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL?

SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL in stock?

SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL?

SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e1010df/msds/bncb3811-500.pdf.

What is SOX2 (Embryonic Stem Cell Marker) (SOX2/3811R), Biotin conjugate, 0.1mg/mL used for?

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a plur

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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