TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL

Catalog number BNC043813-500

Price for BNC043813-500

Size / count 1x 500 µL

About this product

Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC043813-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: MSA; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TPO
Gene ID: 7173
NCBI Gene ID: 467554
UniProt: P07202
Swiss Prot: P07202
Host: Rabbit
Species Reactivity: Human
Reactivity: Thyroid Peroxidase|TPO
Immunogen: Recombinant fragment of human TPO (around aa 685-804) (Exact sequence is proprietary)
Target Antigen: Thyroid Peroxidase | TPO
Clonality: Recombinant Monoclonal
Clone: TPO/3813R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Thyroid Carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL?

The catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL is BNC043813-500.

What sizes are available for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL in stock?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL?

The safety data sheet for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a2061270361e10475a/msds/bnc043813-500.pdf.

What is TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF405S conjugate, 0.1mg/mL used for?

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.