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Product details
Catalog number BNC943813-100
Price for BNC943813-100
Size / count 1x 100 µL
Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF594 conjugate, 0.1mg/mL is BNC943813-100.
TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e10314f/msds/bnc943813-100.pdf.
Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
