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Product details

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL

Catalog number BNUB3813-100

Price for BNUB3813-100

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Size / count 1x 100 µL

About this product

Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB3813-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
MSA; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TPO
Gene ID
7173
NCBI Gene ID
467554
UniProt
P07202
Swiss Prot
P07202
Host
Rabbit
Species Reactivity
Human
Reactivity
Thyroid Peroxidase|TPO
Immunogen
Recombinant fragment of human TPO (around aa 685-804) (Exact sequence is proprietary)
Target Antigen
Thyroid Peroxidase | TPO
Clonality
Recombinant Monoclonal
Clone
TPO/3813R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Thyroid Carcinoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL?

The catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL is BNUB3813-100.

What sizes are available for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL in stock?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL?

TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL?

Estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL?

The safety data sheet for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100721/msds/bnub3813-100.pdf.

What is TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/3813R), 0.2mg/mL used for?

Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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