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Product details

Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL

Catalog number BNC683912-100

Price for BNC683912-100

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Size / count 1x 100 µL

About this product

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H) . Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC683912-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
NEFH; Neurofilament H; Neurofilament Heavy Polypeptide 200kDa; Neurofilament Triplet H Protein; NF-H; NF200. 68kDa neurofilament protein; Light molecular weight neurofilament protein; NEFL; Neurofilament light polypeptide 68kDa; Neurofilament light polypeptide; Neurofilament protein; light chain; Neurofilament subunit NF-L; Neurofilament triplet L protein; NF-L; NF68
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NEFH; NEFL
Gene ID
4744
NCBI Gene ID
198760
UniProt
P12036
Swiss Prot
P12036
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Neurofilament H L
Immunogen
Human NF-H from isolated brain cells
Target Antigen
Neurofilament H L
Clonality
Monoclonal
Clone
2F11
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cytoskeleton, Neuroscience
Positive Control
IMR-32 cells. Cerebellum or Neuroblastoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
200 kDa & 68 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL?

The catalog number for Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL is BNC683912-100.

What sizes are available for Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL in stock?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e107055/msds/bnc683912-100.pdf.

What is Neurofilament (H+L) (Neuronal Marker) (2F11), CF568 conjugate, 0.1mg/mL used for?

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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