Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL

Catalog number BNC883912-100

Price for BNC883912-100

Size / count 1x 100 µL

About this product

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H) . Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC883912-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: NEFH; Neurofilament H; Neurofilament Heavy Polypeptide 200kDa; Neurofilament Triplet H Protein; NF-H; NF200. 68kDa neurofilament protein; Light molecular weight neurofilament protein; NEFL; Neurofilament light polypeptide 68kDa; Neurofilament light polypeptide; Neurofilament protein; light chain; Neurofilament subunit NF-L; Neurofilament triplet L protein; NF-L; NF68
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NEFH; NEFL
Gene ID: 4744
NCBI Gene ID: 198760
UniProt: P12036
Swiss Prot: P12036
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Reactivity: Neurofilament H L
Immunogen: Human NF-H from isolated brain cells
Target Antigen: Neurofilament H L
Clonality: Monoclonal
Clone: 2F11
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Cytoskeleton, Neuroscience
Positive Control: IMR-32 cells. Cerebellum or Neuroblastoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 200 kDa & 68 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL?

The catalog number for Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL is BNC883912-100.

What sizes are available for Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL in stock?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a6061270361e105fc7/msds/bnc883912-100.pdf.

What is Neurofilament (H+L) (Neuronal Marker) (2F11), CF488A conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.