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Product details

Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL

Catalog number BNC943912-100

Price for BNC943912-100

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Size / count 1x 100 µL

About this product

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H) . Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC943912-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
NEFH; Neurofilament H; Neurofilament Heavy Polypeptide 200kDa; Neurofilament Triplet H Protein; NF-H; NF200. 68kDa neurofilament protein; Light molecular weight neurofilament protein; NEFL; Neurofilament light polypeptide 68kDa; Neurofilament light polypeptide; Neurofilament protein; light chain; Neurofilament subunit NF-L; Neurofilament triplet L protein; NF-L; NF68
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NEFH; NEFL
Gene ID
4744
NCBI Gene ID
198760
UniProt
P12036
Swiss Prot
P12036
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Neurofilament H L
Immunogen
Human NF-H from isolated brain cells
Target Antigen
Neurofilament H L
Clonality
Monoclonal
Clone
2F11
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cytoskeleton, Neuroscience
Positive Control
IMR-32 cells. Cerebellum or Neuroblastoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
200 kDa & 68 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL?

The catalog number for Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL is BNC943912-100.

What sizes are available for Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL in stock?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL?

Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e1025ae/msds/bnc943912-100.pdf.

What is Neurofilament (H+L) (Neuronal Marker) (2F11), CF594 conjugate, 0.1mg/mL used for?

This MAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H NF-L) . Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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