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Product details

Human SCF Recombinant Rabbit Monoclonal Antibody [PSH07-58] - BSA and Azide free (Detector)

Catalog number HA722872

Price for HA722872

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Size / count 100 µL

About this product

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

Specifications

Catalog number
HA722872
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
C kit ligand antibody C-kit ligand antibody Ckit ligand antibody DCUA antibody DFNA69 antibody DKFZp686F2250 antibody familial progressive hyperpigmentation 2 antibody FPH2 antibody FPHH antibody KIT ligand antibody Kitl antibody KITLG antibody KL 1 antibody KL1 antibody Mast cell growth factor antibody MGF antibody MGF stem cell factor antibody SCF antibody SCF_HUMAN antibody SF antibody SHEP7 antibody sKITLG antibody Soluble KIT ligand antibody Steel factor antibody steel, mouse, homolog of antibody Stem cell factor antibody Stem cell factor precursor antibody
Abbreviation
Kit ligand Mast cell growth factor MGF Stem cell factor c-Kit ligand Soluble KIT ligand (sKITLG) KITLG MGF, SCF
Swiss Prot
P21583 Human
Cellular Locus
Extracellular.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human SCF aa 26-214 (HA210618).
Isotype
IgG
Clone
PSH07-58
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
ELISA (Det)
Positive Control
Recombinant Human SCF protein (HA210618).
Concentration
1 mg/mL
Dilution
ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH07-57] to Human SCF antibody (Capture) (HA722871) and recombinant Human SCF protein as the standard (HA210618). The reference range value is 12.3-3,000 pg/ml.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Human SCF Recombinant Rabbit Monoclonal Antibody [PSH07-58] - BSA and Azide free (Detector)?

The catalog number for Human SCF Recombinant Rabbit Monoclonal Antibody [PSH07-58] - BSA and Azide free (Detector) is HA722872.

What sizes are available for Human SCF Recombinant Rabbit Monoclonal Antibody [PSH07-58] - BSA and Azide free (Detector)?

Human SCF Recombinant Rabbit Monoclonal Antibody [PSH07-58] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human SCF Recombinant Rabbit Monoclonal Antibody [PSH07-58] - BSA and Azide free (Detector) in stock?

Human SCF Recombinant Rabbit Monoclonal Antibody [PSH07-58] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human SCF Recombinant Rabbit Monoclonal Antibody [PSH07-58] - BSA and Azide free (Detector) used for?

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several sig

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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