Hsp70 Recombinant Rabbit Monoclonal Antibody [PD01-65]

Catalog number HA721497

Price for HA721497

Size / count 100 µL

About this product

The 70 kilodalton heat shock proteins (Hsp70s) are a family of conserved ubiquitously expressedheat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress. When not interacting with a substrate peptide, Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity, such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes, the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues, and interacts with them. This spontaneous interaction is reversible, and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However, the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70, increasing its normally slow rate of ATP hydrolysis.

Specifications

Catalog number: HA721497
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: DnaK type molecular chaperone HSP70 1 antibody Epididymis secretory protein Li 103 antibody FLJ54303 antibody FLJ54370 antibody FLJ54392 antibody FLJ54408 antibody FLJ75127 antibody Heat shock 70 kDa protein 1 antibody Heat shock 70 kDa protein 1/2 antibody Heat shock 70 kDa protein 1A/1B antibody Heat shock 70kDa protein 1A antibody Heat shock 70kDa protein 1B antibody Heat shock induced protein antibody HEL S 103 antibody HSP70 1 antibody HSP70 1B antibody HSP70 2 antibody HSP70-1/HSP70-2 antibody HSP70-1A antibody HSP70.1 antibody HSP70.1/HSP70.2 antibody HSP70I antibody HSP71_HUMAN antibody HSP72 antibody HSPA1 antibody HSPA1A antibody HSPA1B antibody
Abbreviation: HSP70-2, HSP70.2
Swiss Prot: P0DMV9 Human, P0DMV8 Human, P17879 Mouse, Q61696 Mouse, Q07439 Rat
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant fragment within Human Hsp70 aa 50-300.
Isotype: IgG
Clone: PD01-65
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HCT 116 cell lysate, HEK-293 cell lysate, HepG2 cell lysate, A431 cell lysate, A549 cell lysate, human breast carcinoma tissue, human liver carcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 70 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Hsp70 Recombinant Rabbit Monoclonal Antibody [PD01-65]?

The catalog number for Hsp70 Recombinant Rabbit Monoclonal Antibody [PD01-65] is HA721497.

What sizes are available for Hsp70 Recombinant Rabbit Monoclonal Antibody [PD01-65]?

Hsp70 Recombinant Rabbit Monoclonal Antibody [PD01-65] is available in the following size(s): 100 µL.

Is Hsp70 Recombinant Rabbit Monoclonal Antibody [PD01-65] in stock?

Hsp70 Recombinant Rabbit Monoclonal Antibody [PD01-65] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Hsp70 Recombinant Rabbit Monoclonal Antibody [PD01-65] used for?

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.