Human IL-33 Recombinant Rabbit Monoclonal Antibody [PSH03-06] - BSA and Azide free (Detector)

Catalog number HA721936

Price for HA721936

Size / count 100 µL

About this product

Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. Induces rapid UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages. In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets.

Specifications

Catalog number: HA721936
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: C9orf26 antibody CHROMOSOME 9 OPEN READING FRAME 26 antibody DKFZp586H0523 antibody DVS27 antibody DVS27 related protein antibody IL 1F11 antibody IL 33 antibody IL-1F11 antibody IL-33 antibody IL1F11 antibody IL33 antibody IL33_HUMAN antibody Interleukin 1 family member 11 antibody Interleukin 33 antibody INTERLEUKIN 33 NFHEV antibody Interleukin 33 precursor antibody Interleukin-1 family member 11 antibody Interleukin-33 (109-270) antibody Interleukin33 antibody NF HEV antibody NF-HEV antibody NFEHEV antibody NFHEV antibody Nuclear factor for high endothelial venules antibody Nuclear factor from high endothelial venules antibody OTTHUMP00000021041 antibody RP11 575C20.2 antibody
Abbreviation: Interleukin-33 IL-33 Interleukin-1 family member 11 (IL-1F11) Nuclear factor from high endothelial venules (NF-HEV) IL33 C9orf26, IL1F11, NFHEV
Swiss Prot: O95760 Human
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human IL-33 aa 109-270.
Isotype: IgG
Clone: PSH03-06
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Det)
Positive Control: Recombinant standard Human Human IL-33 (HA210539).
Concentration: 1 mg/mL
Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH03-05] to Human Human IL-33 (Capture) (HA721935) and recombinant standard Human Human IL-33 (HA210539) as the standard. The reference range value is 37-1000 pg/ml.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Molecular Weight: Predicted band size: 30.8 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Human IL-33 Recombinant Rabbit Monoclonal Antibody [PSH03-06] - BSA and Azide free (Detector)?

The catalog number for Human IL-33 Recombinant Rabbit Monoclonal Antibody [PSH03-06] - BSA and Azide free (Detector) is HA721936.

What sizes are available for Human IL-33 Recombinant Rabbit Monoclonal Antibody [PSH03-06] - BSA and Azide free (Detector)?

Human IL-33 Recombinant Rabbit Monoclonal Antibody [PSH03-06] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human IL-33 Recombinant Rabbit Monoclonal Antibody [PSH03-06] - BSA and Azide free (Detector) in stock?

Human IL-33 Recombinant Rabbit Monoclonal Antibody [PSH03-06] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human IL-33 Recombinant Rabbit Monoclonal Antibody [PSH03-06] - BSA and Azide free (Detector) used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.