CCL4/MIP-1 beta Recombinant Rabbit Monoclonal Antibody [JE33-21]

About this product

Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B.

Specifications

Catalog number

HA721904

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

MIP 1 beta antibody Secreted protein G 26 antibody ACT 2 antibody ACT-2 antibody ACT2 antibody AT744.1 antibody AT744.2 antibody C C motif chemokine 4 antibody C C motif chemokine 4 like antibody C C motif chemokine ligand 4 like 1 antibody C C motif chemokine ligand 4 like 2 antibody CC chemokine ligand 4 antibody CC chemokine ligand 4L1 antibody CC chemokine ligand 4L1d2 antibody CC chemokine ligand 4L2 antibody CCL4 antibody CCL4_HUMAN antibody ccl4l 1 antibody CCL4L antibody CCL4L1 antibody Chemokine (C C motif) ligand 4 antibody Chemokine (C C motif) ligand 4 like 1 antibody Chemokine (C C motif) ligand 4 like 1, telomeric antibody Chemokine (C C motif) ligand 4 like 2 antibody Chemokine CC Motif Ligand 4 antibody G 26 antibody G 26 T lymphocyte secreted protein antibody G-26 T-lymphocyte-secreted protein antibody HC21 antibody Immune activation 2 antibody LAG 1 antibody LAG-1 antibody LAG1 antibody Lymphocyte activation gene 1 antibody Lymphocyte activation gene 1 protein antibody Macrophage inflammatory protein 1 beta antibody Macrophage inflammatory protein 1-beta antibody Macrophage inflammatory protein 1b2 antibody MGC104418 antibody MGC126025 antibody MGC126026 antibody MIP-1-beta antibody MIP-1-beta (1-69) antibody MIP-1-beta (3-69) antibody MIP1 beta antibody MIP1B antibody MIP1B1 antibody Monocyte adherence induced protein 5 alpha antibody PAT 744 antibody Protein H400 antibody SCYA2 antibody SCYA4 antibody SCYA4L antibody SCYA4L1 antibody SCYA4L2 antibody SCYQ4L2 antibody Secreted protein G 26 antibody Secreted protein G26 antibody SIS gamma antibody SIS-gamma antibody Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody Small inducible cytokine A4 antibody small inducible cytokine A4-like antibody Small-inducible cytokine A4 antibody T cell activation protein 2 antibody T-cell activation protein 2 antibody

Abbreviation

C-C motif chemokine 4 G-26 T-lymphocyte-secreted protein HC21 Lymphocyte activation gene 1 protein (LAG-1) MIP-1-beta (1-69) Macrophage inflammatory protein 1-beta (MIP-1-beta) PAT 744 Protein H400 SIS-gamma Small-inducible cytokine A4 T-cell activation protein 2 (ACT-2) CCL4 LAG1, MIP1B, SCYA4

Swiss Prot

P13236 Human, Q8NHW4 Human, P14097 Mouse

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide within Human CCL4/MIP-1 beta aa 1-50 / 92.

Isotype

IgG

Clone

JE33-21

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB

Positive Control

THP-1 treated with 100nM TPA overnight then add 100ng/mL LPS for 7 hours then add 1μg/mL BFA for 3 hours cell lysate, RAW264.7 treated with 100nM TPA overnight then add 100ng/mL LPS for 7 hours then add 1μg/mL BFA for 3 hours cell lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 12 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes