MFGE8 Recombinant Rabbit Monoclonal Antibody [PSH05-75]

Catalog number HA722442

Price for HA722442

Size / count 100 µL

About this product

Milk fat globule-EGF factor 8 protein (Mfge8), also known as lactadherin, is a protein that in humans is encoded by the MFGE8 gene. Mfge8 is a secreted protein found in vertebrates, including mammals as well as birds. MFGE8 may function as a cell adhesion protein to connect smooth muscle to elastic fibers in arteries. An amyloid fragment of MFGE8 known as medin accumulates in the aorta with aging. MFGE8 in the vasculature of adults can induce recovery from ischemia by facilitating angiogenesis. It has been suggested that antagonizing MFGE8-induced angiogenesis could be a way of fighting cancer. MFGE8 contains a phosphatidylserine (PS) binding domain, as well as an arginine-glycine-aspartic acid motif, which enables the binding to integrins. MFGE8 binds PS, which is exposed on the surface of apoptotic cells. Opsonization of the apoptotic cells and binding to integrins on the surface of phagocytic cells, mediates the engulfment of the dead cell.

Specifications

Catalog number: HA722442
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: BA46 antibody Breast epithelial antigen BA46 antibody EDIL1 antibody HMFG antibody hP47 antibody HsT19888 antibody Lactadherin antibody Medin antibody MFG-E8 antibody MFGE8 antibody MFGM antibody MFGM_HUMAN antibody Milk fat globule EGF factor 8 antibody Milk fat globule EGF factor 8 protein antibody Milk fat globule-EGF factor 8 antibody O acetyl disialoganglioside synthase antibody OAcGD3S antibody SED1 antibody SPAG10 antibody Sperm associated antigen 10 antibody Sperm surface protein hP47 antibody
Abbreviation: MFGE8
Swiss Prot: Q08431 Human, P21956 Mouse, P70490 Rat
Cellular Locus: Membrane, Secreted, Cytoplasmic vesicle, secretory vesicle, acrosome membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human MFGE8 aa 1-387.
Isotype: IgG
Clone: PSH05-75
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: A549 cell lysate, A431 cell lysate, HeLa cell lysate, MCF7 cell lysate, SK-Br-3 cell lysate, BT-20 cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 43 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for MFGE8 Recombinant Rabbit Monoclonal Antibody [PSH05-75]?

The catalog number for MFGE8 Recombinant Rabbit Monoclonal Antibody [PSH05-75] is HA722442.

What sizes are available for MFGE8 Recombinant Rabbit Monoclonal Antibody [PSH05-75]?

MFGE8 Recombinant Rabbit Monoclonal Antibody [PSH05-75] is available in the following size(s): 100 µL.

Is MFGE8 Recombinant Rabbit Monoclonal Antibody [PSH05-75] in stock?

MFGE8 Recombinant Rabbit Monoclonal Antibody [PSH05-75] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MFGE8 Recombinant Rabbit Monoclonal Antibody [PSH05-75] used for?

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.