Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-62] - BSA and Azide free (Detector)

Catalog number HA722878

Price for HA722878

Size / count 100 µL

About this product

Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage. In addition, plays a role in immune response and possesses antiviral activity against various viruses such as vesicular stomatitis virus, influenza A virus (H1N1) and human herpes virus 1. Mechanistically, translocates from the cytoplasm into the cell nucleus upon virus infection to influence NF-kappa-B activities.

Specifications

Catalog number: HA722878
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CHDS6 antibody Matrix metalloproteinase 3 antibody Matrix metalloproteinase 3 preproprotein antibody Matrix metalloproteinase-3 antibody MGC126102 antibody MGC126103 antibody MGC126104 antibody MMP 3 antibody MMP-3 antibody MMP3 antibody MMP3_HUMAN antibody Proteoglycanase antibody SL-1 antibody SL1 antibody STMY antibody STMY1 antibody STR1 antibody Stromelisin 1 antibody Stromelysin 1 antibody Stromelysin 1 progelatinase antibody Stromelysin-1 antibody Transin 1 antibody Transin-1 antibody
Abbreviation: Stromelysin-1 SL-1 Matrix metalloproteinase-3 (MMP-3) Transin-1 MMP3 STMY1
Swiss Prot: P08254 Human
Cellular Locus: Secreted
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human MMP-3 aa18-477 (HA210853).
Isotype: IgG
Clone: PSH07-62
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Det)
Positive Control: Recombinant Human MMP-3 protein (HA210853).
Concentration: 1 mg/mL
Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH07-61] to Human MMP-3 antibody (Capture) (HA722877) and recombinant Human MMP-3 protein as the standard (HA210853). The reference range value is 41.2-10,000 pg/ml.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-62] - BSA and Azide free (Detector)?

The catalog number for Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-62] - BSA and Azide free (Detector) is HA722878.

What sizes are available for Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-62] - BSA and Azide free (Detector)?

Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-62] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-62] - BSA and Azide free (Detector) in stock?

Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-62] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human MMP-3 Recombinant Rabbit Monoclonal Antibody [PSH07-62] - BSA and Azide free (Detector) used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.