IGF1 Receptor Antibody

About this product

<font size="3">IGF1 Receptor Antibody (IGF1R Antibody) is a rabbit polyclonal antibody designed to detect endogenous levels of total Insulin-like Growth Factor 1 Receptor (IGF1R/CD221). IGF1R is a receptor tyrosine kinase involved in cell growth, survival, metabolism and signaling pathways associated with insulin-like growth factors. This antibody recognizes a C-terminal region of human IGF1R and is suitable for Western blot analysis in human, mouse and rat samples, making it useful for research in IGF1 signaling, cancer biology, cell proliferation and receptor tyrosine kinase pathways.</font><br>

Specifications

Catalog number

AF7709-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

<font size="3">9007-83-4</font>

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

<font size="3">A synthesized peptide derived from human IGF1 Receptor, corresponding to a region within C-terminal amino acids.</font>

Clonality

Polyclonal

Isotype

IgG

Conjugation

<font size="3">Unconjugated</font>

Applications

<font size="3">WB</font>

Purification

<font size="3">The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).</font>

Dilution

<font size="3">WB 1:500-1:2000</font>

Form

<font size="3">Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.</font>

Specificity

<font size="3">IGF1 Receptor Antibody detects endogenous levels of total IGF1 Receptor.</font>

FAQ

<font size="3"><b><font color="#0015ab">What is IGF1R? =&gt; </font></b>IGF1R, also known as IGF1 Receptor or CD221, is a transmembrane receptor tyrosine kinase that mediates signaling triggered by insulin-like growth factors. <b><font color="#0015ab">What does this IGF1R antibody detect? </font></b><span style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5); font-weight: bolder;"><font color="#0015ab" style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5);">=&gt; </font></span>It detects endogenous levels of total IGF1 Receptor rather than a specific phosphorylated form. <b><font color="#0015ab">Can this antibody be used for Western blot? </font></b><span style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5); font-weight: bolder;"><font color="#0015ab" style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5);">=&gt; </font></span>Yes. It is validated for Western blot, with a recommended dilution range of 1:500–1:2000. <b><font color="#0015ab">Which species are reactive? </font></b><span style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5); font-weight: bolder;"><font color="#0015ab" style="border-color: oklch(0.922 0 0); outline-color: oklab(0.708 0 0 / 0.5);">=&gt; </font></span>The antibody is reactive with human, mouse and rat samples.</font>

Prediction Reactivity

<font size="3">Bovine, Rabbit, Dog, Chicken, Xenopus</font>