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Product details

Lysozyme Recombinant Mouse Monoclonal Antibody [A5A8-R]

Catalog number HA601229

Price for HA601229

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Size / count 100 µL

About this product

Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase, is an antimicrobial enzyme produced by animals that forms part of the innate immune system. Lysozyme is a glycoside hydrolase that catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan, which is the major component of gram-positive bacterial cell wall. Lysozyme is abundant in secretions including tears, saliva, human milk, and mucus. It is also present in cytoplasmic granules of the macrophages and the polymorphonuclear neutrophils (PMNs). Large amounts of lysozyme can be found in egg white. C-type lysozymes are closely related to alpha-lactalbumin in sequence and structure, making them part of the same glycoside hydrolase family 22. In humans, the C-type lysozyme enzyme is encoded by the LYZ gene. In certain cancers (especially myelomonocytic leukemia) excessive production of lysozyme by cancer cells can lead to toxic levels of lysozyme in the blood. High lysozyme blood levels can lead to kidney failure and low blood potassium, conditions that may improve or resolve with treatment of the primary malignancy. Serum lysozyme is much less specific for diagnosis of sarcoidosis than serum angiotensin converting enzyme; however, since it is more sensitive, it is used as a marker of sarcoidosis disease activity and is suitable for disease monitoring in proven cases.

Specifications

Catalog number
HA601229
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
1 4 beta N acetylmuramidase C antibody 1 antibody 4-beta-N-acetylmuramidase C antibody EC 3.2.1.17 antibody LYSC_HUMAN antibody Lysosyme antibody Lysozyme (renal amyloidosis) antibody Lysozyme C antibody Lysozyme C precursor antibody LYZ antibody LZM antibody Renal amyloidosis antibody
Abbreviation
LYZ
Swiss Prot
P61626 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within Human Lysozyme aa 1-141 / 148.
Isotype
IgG1
Clone
A5A8-R
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HL-60 cell lysate, U-937 cell lysate, human spleen tissue, human stomach cancer tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 17 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Lysozyme Recombinant Mouse Monoclonal Antibody [A5A8-R]?

The catalog number for Lysozyme Recombinant Mouse Monoclonal Antibody [A5A8-R] is HA601229.

What sizes are available for Lysozyme Recombinant Mouse Monoclonal Antibody [A5A8-R]?

Lysozyme Recombinant Mouse Monoclonal Antibody [A5A8-R] is available in the following size(s): 100 µL.

Is Lysozyme Recombinant Mouse Monoclonal Antibody [A5A8-R] in stock?

Lysozyme Recombinant Mouse Monoclonal Antibody [A5A8-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Lysozyme Recombinant Mouse Monoclonal Antibody [A5A8-R] used for?

Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase, is an antimicrobial enzyme produced by animals that forms part of the innate immune system. Lysozyme is a glycoside hydrolase that catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosa

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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