Cynomolgus ACE2 / ACEH Protein, His Tag

Catalog number AC2-C52H7-1mg

Discontinued

Price for AC2-C52H7-1mg

Size / count 1 mg

This variant is discontinued and cannot be added to your cart.

About this product

Cynomolgus ACE2, His Tag (AC2-C52H7) is expressed from human 293 cells (HEK293) . It contains AA Gln 18 - Thr 741 (Accession # A0A2K5X283-1) .

Specifications

Catalog number: AC2-C52H7-1mg
Size / count: 1 mg
Dry ice: Yes
Hazardous: No
Discontinued: Yes
Background: Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.
Specifications: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 85.7 kDa. The protein migrates as 90-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number: A0A2K5X283-1
Expression Region: Gln 18 - Thr 741
Host: HEK293
Target: ACE2
Conjugation: Unconjugated
Tag: N-10xHis
Source: Cynomolgus
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin: 1.0 EU per μg
Purity: 95%
Bioactivity: Immobilized Cynomolgus ACE2, His Tag (Cat. No. AC2-C52H7) at 2 μg/mL (100 μL/well) can bind Biotinylated SARS-CoV-2 S protein RBD, His,Avitag (Cat. No. SPD-C82E9) with a linear range of 2-78 ng/mL (QC tested).
Format: Liquid
Buffer: 50 mM Tris, 150 mM NaCl, Arginine, pH7.5
Additives: Glycerol
Molecular Weight: 85.7 kDa
Shipping Conditions: Dry ice
Storage Conditions: -70°C
Package Size: 1mg*1
Species: Cynomolgus

Frequently Asked Questions

What is the catalog number for Cynomolgus ACE2 / ACEH Protein, His Tag?

The catalog number for Cynomolgus ACE2 / ACEH Protein, His Tag is AC2-C52H7-1mg.

Is Cynomolgus ACE2 / ACEH Protein, His Tag in stock?

Cynomolgus ACE2 / ACEH Protein, His Tag is currently made to order / not held in immediate stock. Contact us for lead time.

What are the weight and dimensions of Cynomolgus ACE2 / ACEH Protein, His Tag?

Cynomolgus ACE2 / ACEH Protein, His Tag has the following package details: 1mg*1.

Are there any special shipping requirements for Cynomolgus ACE2 / ACEH Protein, His Tag?

Cynomolgus ACE2 / ACEH Protein, His Tag is requires dry ice shipping.

Who manufactures Cynomolgus ACE2 / ACEH Protein, His Tag?

Cynomolgus ACE2 / ACEH Protein, His Tag is manufactured by CRB.

What is the estimated delivery time for Cynomolgus ACE2 / ACEH Protein, His Tag?

Estimated delivery time for Cynomolgus ACE2 / ACEH Protein, His Tag is approximately 10 business day(s), depending on your location.

What is Cynomolgus ACE2 / ACEH Protein, His Tag used for?

Cynomolgus ACE2, His Tag (AC2-C52H7) is expressed from human 293 cells (HEK293) . It contains AA Gln 18 - Thr 741 (Accession # A0A2K5X283-1) .

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.