Mouse NODAL Protein, Tag Free

About this product

Mouse NODAL Protein, Tag Free (NOL-M5133) is expressed from E. coli cells. It contains AA His 245 - Leu 354 (Accession # P43021).

Specifications

Catalog number

NOL-M5133-50ug

Size / count

50 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016]

Specifications

This protein carries no "tag". The protein has a calculated MW of 12.8 kDa.

Expression Region

His 245 - Leu 354

Host

E. coli

Origin Species

Mouse

Target

NODAL

Conjugation

Unconjugated

Tag

Native

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Format

Powder

Molecular Weight

12.8 kDa

Shipping Conditions

Room Temperature

Storage Conditions

-20°C