Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin

Catalog number NKD-H5257-100ug

Discontinued

Price for NKD-H5257-100ug

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Human NKG2D, Llama IgG2b Fc Tag (NKD-H5257) is expressed from human 293 cells (HEK293). It contains AA Ile 73 - Val 216 (Accession # P26718-1).

Specifications

Catalog number: NKD-H5257-100ug
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: NKG2D is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors, also known as KLRK1, CD314, D12S2489E, KLR and killer cell lectin like receptor K1. NKG2D itself forms a homodimer whose ectodomains serve for ligand binding. NKG2D is a major recognition receptor for the detection and elimination of transformed and infected cells as its ligands are induced during cellular stress, either as a result of infection or genomic stress such as in cancer. In NK cells, NKG2D serves as an activating receptor, which itself is able to trigger cytotoxicity. The function of NKG2D on CD8+ T cells is to send co-stimulatory signals to activate them.
Specifications: This protein carries a llama IgG2b Fc tag at the N-terminus. The protein has a calculated MW of 44.5 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Ile 73 - Val 216
Host: HEK 293
Target: NKG2D
Conjugation: Unconjugated
Tag: N-LlamaFc(LlamaIgG2b)
Source: Human
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 0.01 EU per μg
Purity: 95%
Bioactivity: Immobilized Human MICA, His Tag (Cat. No. MIA-H5221) at 5 μg/mL (100 μL/well) can bind Human NKG2D, Llama IgG2b Fc Tag (Cat. No. NKD-H5257) with a linear range of 0.01-0.625 μg/mL (QC tested).
Format: Powder
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives: Trehalose
Molecular Weight: 44.5 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin?

The catalog number for Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin is NKD-H5257-100ug.

Is Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin in stock?

Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin?

Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin is manufactured by CRB.

What is the estimated delivery time for Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin?

Estimated delivery time for Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin is approximately 10 business day(s), depending on your location.

What is Human NKG2D / CD314 Protein, Llama IgG2b Fc Tag, low endotoxin used for?

Human NKG2D, Llama IgG2b Fc Tag (NKD-H5257) is expressed from human 293 cells (HEK293). It contains AA Ile 73 - Val 216 (Accession # P26718-1).

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.