Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag

Catalog number LI4-C5250-100ug

Discontinued

Price for LI4-C5250-100ug

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Cynomolgus LILRB4, Mouse IgG2a Fc Tag (LI4-C5250) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Glu 259 (Accession # XP_015297198.1).

Specifications

Catalog number: LI4-C5250-100ug
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Specifications: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 53.2 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Gln 22 - Glu 259
Host: HEK 293
Target: LILRB4
Conjugation: Unconjugated
Tag: C-mFc(mIgG2a)
Source: Cynomolgus
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 1.0 EU per μg
Purity: 95%
Format: Powder
Buffer: 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Additives: Trehalose
Molecular Weight: 53.2 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag?

The catalog number for Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag is LI4-C5250-100ug.

Is Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag in stock?

Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag?

Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag is manufactured by CRB.

What is the estimated delivery time for Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag?

Estimated delivery time for Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag is approximately 10 business day(s), depending on your location.

What is Cynomolgus LILRB4 / CD85k / ILT3 Protein, Mouse IgG2a Fc Tag used for?

Cynomolgus LILRB4, Mouse IgG2a Fc Tag (LI4-C5250) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Glu 259 (Accession # XP_015297198.1).

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.