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Product details

Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag

Catalog number EM2-H5142-1mg

Discontinued

Price for EM2-H5142-1mg

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Size / count 1 mg

This variant is discontinued and cannot be added to your cart.

About this product

Human AIMP1, His Tag (EM2-H5142) is expressed from E. coli cells. It contains AA Ala 2 - Lys 312 (Accession # Q12904-1).

Specifications

Catalog number
EM2-H5142-1mg
Size / count
1 mg
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.
Specifications
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 35.2 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE).
Expression Region
Ala 2 - Lys 312
Host
E. coli
Target
AIMP1
Conjugation
Unconjugated
Tag
N-6×His
Source
Human
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
35.2 kDa
Shipping Conditions
Room Temperature
Storage Conditions
-20°C

Frequently Asked Questions

What is the catalog number for Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag?

The catalog number for Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag is EM2-H5142-1mg.

Is Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag in stock?

Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag?

Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag is manufactured by CRB.

What is the estimated delivery time for Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag?

Estimated delivery time for Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag is approximately 10 business day(s), depending on your location.

What is Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag used for?

Human AIMP1, His Tag (EM2-H5142) is expressed from E. coli cells. It contains AA Ala 2 - Lys 312 (Accession # Q12904-1).

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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