Rat LIF Protein, His Tag (MALS verified)

Catalog number LIF-R52H3-1mg

Discontinued

Price for LIF-R52H3-1mg

Size / count 1 mg

This variant is discontinued and cannot be added to your cart.

About this product

Rat LIF, His Tag (LIF-R52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 23 - Phe 202 (Accession # P17777-1).

Specifications

Catalog number: LIF-R52H3-1mg
Size / count: 1 mg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.
Specifications: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.7 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Ser 23 - Phe 202
Host: HEK 293
Target: LIF
Conjugation: Unconjugated
Tag: C-10×His
Source: Rat
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 1.0 EU per μg
Purity: 95%
Format: Powder
Buffer: PBS, pH7.4
Additives: Trehalose
Molecular Weight: 21.7 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for Rat LIF Protein, His Tag (MALS verified)?

The catalog number for Rat LIF Protein, His Tag (MALS verified) is LIF-R52H3-1mg.

Is Rat LIF Protein, His Tag (MALS verified) in stock?

Rat LIF Protein, His Tag (MALS verified) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Rat LIF Protein, His Tag (MALS verified)?

Rat LIF Protein, His Tag (MALS verified) is manufactured by CRB.

What is the estimated delivery time for Rat LIF Protein, His Tag (MALS verified)?

Estimated delivery time for Rat LIF Protein, His Tag (MALS verified) is approximately 10 business day(s), depending on your location.

What is Rat LIF Protein, His Tag (MALS verified) used for?

Rat LIF, His Tag (LIF-R52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 23 - Phe 202 (Accession # P17777-1).

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.