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Product details

SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag

Catalog number NUN-C52Ha-100ug

Discontinued

Price for NUN-C52Ha-100ug

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Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

SARS-CoV-2 Nucleocapsid protein, His Tag (NUN-C52Ha) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1). Mutations P13L, R203K, G204R, G214C were identified in the SARS-CoV-2 Lambda variant (Pango lineage: C.37).

Specifications

Catalog number
NUN-C52Ha-100ug
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.4 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region
Met 1 - Ala 419
Host
HEK 293
Target
Nucleocapsid protein
Conjugation
Unconjugated
Tag
C-6×His
Source
SARS-CoV-2
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized SARS-CoV-2 Nucleocapsid protein, His Tag (Cat. No. NUN-C52Ha) at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 with a linear range of 0.1-6 ng/mL (QC tested).
Format
Powder
Buffer
PBS, 0.5 M Arginine, pH7.3
Additives
Trehalose
Molecular Weight
47.4 kDa
Shipping Conditions
Room Temperature
Storage Conditions
-20°C

Frequently Asked Questions

What is the catalog number for SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag?

The catalog number for SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag is NUN-C52Ha-100ug.

Is SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag in stock?

SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag?

SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag is manufactured by CRB.

What is the estimated delivery time for SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag?

Estimated delivery time for SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag is approximately 10 business day(s), depending on your location.

What is SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag used for?

SARS-CoV-2 Nucleocapsid protein, His Tag (NUN-C52Ha) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1). Mutations P13L, R203K, G204R, G214C were identified in the SARS-CoV-2 Lambda variant (Pango lineage: C.37).

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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