Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin

Catalog number GIR-H525a-100ug

Discontinued

Price for GIR-H525a-100ug

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Human GITR Protein, Mouse IgG2a Fc Tag (GIR-H525a) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # Q9Y5U5-1).

Specifications

Catalog number: GIR-H525a-100ug
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Specifications: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 41.4 kDa. The protein migrates as 46-49 kDa and 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Gln 26 - Glu 161
Host: HEK 293
Target: GITR
Conjugation: Unconjugated
Tag: C-mFc(mIgG2a)
Source: Human
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 0.1 EU per μg
Purity: 95%
Bioactivity: Immobilized Human GITR Ligand, Fc Tag (Cat. No. GIL-H526a) at 5 μg/mL (100 μL/well) can bind Human GITR Protein, Mouse IgG2a Fc Tag (Cat. No. GIR-H525a) with a linear range of 0.039-0.313 μg/mL (QC tested).
Format: Powder
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Additives: Trehalose
Molecular Weight: 41.4 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin?

The catalog number for Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin is GIR-H525a-100ug.

Is Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin in stock?

Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin?

Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin is manufactured by CRB.

What is the estimated delivery time for Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin?

Estimated delivery time for Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin is approximately 10 business day(s), depending on your location.

What is Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin used for?

Human GITR Protein, Mouse IgG2a Fc Tag (GIR-H525a) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # Q9Y5U5-1).

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.