Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified)

Catalog number ILC-M82E9-25ug

Discontinued

Price for ILC-M82E9-25ug

Size / count 25 µg

This variant is discontinued and cannot be added to your cart.

About this product

Biotinylated Mouse IL-17C, His,Avitag (ILC-M82E9) is expressed from human 293 cells (HEK293). It contains AA Asp 17 - Gln 194 (Accession # Q8K4C5-1).

Specifications

Catalog number: ILC-M82E9-25ug
Size / count: 25 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL‑17C binds to IL‑17 RE with high affinity and to IL‑17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
Specifications: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 23.4 kDa. The protein migrates as 25-27 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Asp 17 - Gln 194
Host: HEK 293
Target: IL-17C
Conjugation: Biotin-labeled
Tag: C-10×His & C-Avi
Source: Mouse
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 1.0 EU per μg
Purity: 95%
Bioactivity: Immobilized Human IL-17 RE (155-454), Fc Tag (Cat. No. ILE-H5256) at 2 μg/mL (100 μL/well) can bind Biotinylated Mouse IL-17C, His,Avitag (Cat. No. ILC-M82E9) with a linear range of 0.2-20 ng/mL (QC tested).
Format: Powder
Buffer: PBS, 0.5 M Arginine, pH7.4
Additives: Trehalose
Molecular Weight: 23.4 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified)?

The catalog number for Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified) is ILC-M82E9-25ug.

Is Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified) in stock?

Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified)?

Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified) is manufactured by CRB.

What is the estimated delivery time for Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified)?

Estimated delivery time for Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified) is approximately 10 business day(s), depending on your location.

What is Biotinylated Mouse IL-17C Protein, His,Avitag™ (MALS verified) used for?

Biotinylated Mouse IL-17C, His,Avitag (ILC-M82E9) is expressed from human 293 cells (HEK293). It contains AA Asp 17 - Gln 194 (Accession # Q8K4C5-1).

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.