Human Glypican 1 / GPC1 (S486A, S488A, S490A) Protein, His Tag (MALS verified)

About this product

Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Specifications

Catalog number

GP1-H52H8-100ug

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 57.9 kDa. The protein migrates as 58-61 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P35052-1 (S486A, S488A, S490A)

Expression Region

Asp 24 - Ser 530

Host

HEK293

Target

Glypican 1

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

50 mM Tris, 150 mM NaCl, pH7.5

Additives

Trehalose

Molecular Weight

57.9 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

P35052-1 (S486A, S488A, S490A)

Preservative

Trehalose