Human GMF-beta Protein, His Tag (MALS verified)

Catalog number GMA-H5145-20ug

Discontinued

Price for GMA-H5145-20ug

Size / count 20 µg

This variant is discontinued and cannot be added to your cart.

About this product

Human GMF-beta, His Tag (GMA-H5145) is expressed from E. coli cells. It contains AA Ser 2 - His 142 (Accession # P60983).

Specifications

Catalog number: GMA-H5145-20ug
Size / count: 20 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Glia Maturation Factor-Beta (GMF-Beta) is a 17 kDa protein nerve gorwth factor identified as a growth and differentiation factor in the vertebrate brain. Glia Maturation Factor-Beta stimulates differentiation of normal neurons as well as glial cells. GMFB inhibits the proliferation of the N-18 neuroblastoma line and the C6 glioma line while promoting their phenotypic expression. GMF-beta inhances the phenotypic expression of glia & neurons thus inhibits the proliferation of their respective tumors when added to cell culture. Although astrocytes produce GMF-b and stores it inside the cells, they don’t secrete the GMF-B into the cultured medium. Cell- surface GMFb acts on the target cells at close range when cells are in direct contact. GMF-Beta is produced by thymic epithelial cells and plays an important role in T cell development in favor of CD4+ T cells. GMF-Beta is a brain-specific protein which belongs to the actin-binding proteins (ADF) family. GMF-beta appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines.
Specifications: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 18.6 kDa. The protein migrates as 19-21 kDa under reducing (R) condition (SDS-PAGE).
Expression Region: Ser 2 - His 142
Host: E. coli
Target: GMF-beta
Conjugation: Unconjugated
Tag: N-10×His
Source: Human
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 0.01 EU per μg
Purity: 95%
Format: Powder
Buffer: PBS, pH7.4
Additives: Trehalose
Molecular Weight: 18.6 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for Human GMF-beta Protein, His Tag (MALS verified)?

The catalog number for Human GMF-beta Protein, His Tag (MALS verified) is GMA-H5145-20ug.

Is Human GMF-beta Protein, His Tag (MALS verified) in stock?

Human GMF-beta Protein, His Tag (MALS verified) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human GMF-beta Protein, His Tag (MALS verified)?

Human GMF-beta Protein, His Tag (MALS verified) is manufactured by CRB.

What is the estimated delivery time for Human GMF-beta Protein, His Tag (MALS verified)?

Estimated delivery time for Human GMF-beta Protein, His Tag (MALS verified) is approximately 10 business day(s), depending on your location.

What is Human GMF-beta Protein, His Tag (MALS verified) used for?

Human GMF-beta, His Tag (GMA-H5145) is expressed from E. coli cells. It contains AA Ser 2 - His 142 (Accession # P60983).

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.