Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (5C5C10) (BQ.1.1/Omicron Specific)

About this product

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Specifications

Catalog number

SPD-Y170-1mg

Size / count

1 mg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

CAS Number

9007-83-4

Host

Hybridoma

Origin Species

Mouse

Target

Spike RBD

Conjugation

Unconjugated

Tag

Mouse IgG1 | Mouse Kappa

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower._x000D_Please avoid repeated freeze-thaw cycles.

Purity

95%

Bioactivity

Immobilized SARS-CoV-2 Spike RBD Protein, His Tag (BQ.1.1/Omicron) (MALS verified) (Cat. No. SPD-C5240) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (5C5C10) (BQ.1.1/Omicron Specific) (Cat. No. SPD-Y170) with a linear range of 0.098-3.125 ng/mL. The antibody does not bind Spike RBD of WT (Cat. No. SPD-C52H3), Alpha (Cat. No. SPD-C52Hn), Beta (Cat. No. SPD-C52Hp), Gamma (Cat. No. SPD-C52Hr), Delta (Cat. No. SPD-C52Hh), B.1.1.529/Omicron (Cat. No. SPD-C522e), BA.2/Omicron (Cat. No. SPD-C522g), BA.3/Omicron (Cat. No. SPD-C522i),BA.4&BA.5/Omicron (Cat. No. SPD-C522r), BA.2.12.1/Omicron (Cat. No. SPD-C522q), BA.2.75/Omicron (Cat. No. SPD-C522t), BF.7&BA.4.6/Omicron (Cat. No. SPD-C522y), XBB/Omicron (Cat. No. SPD-C5241), XBB.1.5/Omicron (Cat. No. SPD-C5242) (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Shipping Conditions

Room Temperature

Storage Conditions

-20°C