Complement factor B Recombinant Rabbit Monoclonal Antibody [JE54-96]

Catalog number HA722704

Price for HA722704

Size / count 100 µL

About this product

Complement factor B is a protein that in humans is encoded by the CFB gene. This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC class III) region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Specifications

Catalog number: HA722704
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: C3/C5 convertase antibody Complement factor B antibody Glycine-rich beta glycoprotein antibody PBF2 antibody Properdin factor B antibody
Abbreviation: CFB, BF, BFD
Swiss Prot: P00751 Human, P04186 Mouse,
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within
Isotype: IgG
Clone: JE54-96
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: Human lung tissue lysate, Mouse lung tissue lysate, Rat lung tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 86 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Complement factor B Recombinant Rabbit Monoclonal Antibody [JE54-96]?

The catalog number for Complement factor B Recombinant Rabbit Monoclonal Antibody [JE54-96] is HA722704.

What sizes are available for Complement factor B Recombinant Rabbit Monoclonal Antibody [JE54-96]?

Complement factor B Recombinant Rabbit Monoclonal Antibody [JE54-96] is available in the following size(s): 100 µL.

Is Complement factor B Recombinant Rabbit Monoclonal Antibody [JE54-96] in stock?

Complement factor B Recombinant Rabbit Monoclonal Antibody [JE54-96] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Complement factor B Recombinant Rabbit Monoclonal Antibody [JE54-96] used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.