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Product details

PSMB2 Recombinant Rabbit Monoclonal Antibody [PSH0-28]

Catalog number HA721308

Price for HA721308

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Size / count 100 µL

About this product

Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7.

Specifications

Catalog number
HA721308
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
HC7 I antibody Macropain subunit C7 I antibody Macropain subunit C7-I antibody Multicatalytic endopeptidase complex subunit C7 1 antibody Multicatalytic endopeptidase complex subunit C7 I antibody Multicatalytic endopeptidase complex subunit C7-I antibody Proteasome (prosome, macropain) subunit beta type 2 antibody Proteasome beta 2 subunit antibody Proteasome component C7 I antibody Proteasome component C7-I antibody Proteasome subunit beta type-2 antibody PSB2_HUMAN antibody Psmb2 antibody
Abbreviation
PSB2 PSMB2
Swiss Prot
P49721 Human
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human PSMB2 aa 175-201/201.
Isotype
IgG
Clone
PSH0-28
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
Jurkat cell lysate, HepG2 cell lysate, HeLa cell lysate, HEK-293 cell lysate, SK-OV-3 cell lysate, HT-29 cell lysate, PC-3M cell lysate.
Concentration
1 mg/mL
Dilution
WB:1:1,000-1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 23 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PSMB2 Recombinant Rabbit Monoclonal Antibody [PSH0-28]?

The catalog number for PSMB2 Recombinant Rabbit Monoclonal Antibody [PSH0-28] is HA721308.

What sizes are available for PSMB2 Recombinant Rabbit Monoclonal Antibody [PSH0-28]?

PSMB2 Recombinant Rabbit Monoclonal Antibody [PSH0-28] is available in the following size(s): 100 µL.

Is PSMB2 Recombinant Rabbit Monoclonal Antibody [PSH0-28] in stock?

PSMB2 Recombinant Rabbit Monoclonal Antibody [PSH0-28] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PSMB2 Recombinant Rabbit Monoclonal Antibody [PSH0-28] used for?

Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 2

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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