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Product details

ARF1 Rabbit Polyclonal Antibody

Catalog number 0807-7

Price for 0807-7

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Size / count 100 µL

About this product

GTP-binding protein involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD). (Microbial infection) Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.

Specifications

Catalog number
0807-7
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
ADP Ribosylation Factor 1 antibody ADP-ribosylation factor 1 antibody ARF 1 antibody ARF1 antibody ARF1_HUMAN antibody
Abbreviation
ADP-ribosylation factor 1,ARF1
Swiss Prot
P84077 Human
Cellular Locus
Cell junction, Cytoplasm, Golgi apparatus, Membrane, Synapse, Synaptosome
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to N terminal Human ARF1.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
HepG2 cell lysate, 293 cell lysate, 293, Hela, HepG2, human liver tissue, human colon cancer tissue, SHSY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,5000;IHC-P: 1:50-1:200;IF-Cell: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
21kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for ARF1 Rabbit Polyclonal Antibody?

The catalog number for ARF1 Rabbit Polyclonal Antibody is 0807-7.

What sizes are available for ARF1 Rabbit Polyclonal Antibody?

ARF1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is ARF1 Rabbit Polyclonal Antibody in stock?

ARF1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is ARF1 Rabbit Polyclonal Antibody used for?

GTP-binding protein involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In i

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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