TdT Rabbit Polyclonal Antibody

Catalog number 0807-9

Price for 0807-9

Size / count 100 µL

About this product

Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase expressed in immature lymphocytes of the thymus and bone marrow, as well as certain leukemic cells. The nuclear enzyme TdT plays a critical role in generating immune receptor diversity. During rearrangement of Ig and TCR V region genes, TdT catalyzes the addition of N nucleotides without a DNA template to V-D and D-J junctions in both Ig and TCR as well as the V-J junctions in the TCR (1–3). During the fetal and newborn period, TdT activity is absent, resulting in an N region-deficient Ag receptor repertoire significantly lacking in the diversity observed in the junctional regions of Igs and TCRs of adult animals

Specifications

Catalog number: 0807-9
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Deoxynucleotidyltransferase terminal antibody DNA nucleotidylexotransferase antibody DNTT antibody Nucleosidetriphosphate DNA deoxynucleotidylexotransferase antibody TDT antibody TDT_HUMAN antibody Terminal addition enzyme antibody Terminal deoxynucleotidyltransferase antibody Terminal deoxyribonucleotidyltransferase antibody Terminal transferase antibody
Abbreviation: Terminal transferase
Swiss Prot: P04053 Human
Cellular Locus: Cell nucleus
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human TdT aa 25-74 / 509.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: Jurkat
Concentration: 1 mg/mL
Dilution: WB: 1:500-1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 58kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for TdT Rabbit Polyclonal Antibody?

The catalog number for TdT Rabbit Polyclonal Antibody is 0807-9.

What sizes are available for TdT Rabbit Polyclonal Antibody?

TdT Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is TdT Rabbit Polyclonal Antibody in stock?

TdT Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is TdT Rabbit Polyclonal Antibody used for?

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.