Autoimmune regulator Rabbit Polyclonal Antibody

Catalog number 0908-2

Price for 0908-2

Size / count 100 µL

About this product

The Autoimmune Regulator (AIRE) is a human transcription factor expressed at higher level in thymus, pancreas, adrenal cortex, and testis. It is expressed at lower level in the spleen, fetal liver and lymph nodes. It contains zinc finger motifs and isoform 1 is localized to both the nucleus and cytoplasm. Three splice variant mRNAs products have been described. In the thymus it causes transcription of a wide selection of organ-specific genes which create proteins that are usually only expressed in peripheral tissues, creating an "immunological self-shadow" in the thymus. Defects in AIRE are a cause of autoimmune poly-endocrinopathy candidiasis ectodermal dystrophy (APECED), also known as autoimmune polyglandular syndrome type I (APS-1).

Specifications

Catalog number: 0908-2
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: AIRE antibody AIRE_HUMAN antibody AIRE1 antibody APECED antibody APECED protein antibody APS1 antibody APSI antibody Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein antibody Autoimmune regulator antibody Autoimmune regulator protein antibody PGA1 antibody
Abbreviation: APECED protein homolog, Aire
Swiss Prot: Q9Z0E3 Mouse, O43918 Human
Cellular Locus: Cell nuclear, cytoplasm
Host: Rabbit
Species Reactivity: Mouse, Human
Immunogen: Synthetic peptide corresponding to Mouse Autoimmune regulator aa 503-552 / 552.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Transfected 293 cells, human pancreatic tissue, mouse pancreatic tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:500 ;IHC-P: 1:100-1:400
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size:59 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Autoimmune regulator Rabbit Polyclonal Antibody?

The catalog number for Autoimmune regulator Rabbit Polyclonal Antibody is 0908-2.

What sizes are available for Autoimmune regulator Rabbit Polyclonal Antibody?

Autoimmune regulator Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Autoimmune regulator Rabbit Polyclonal Antibody in stock?

Autoimmune regulator Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Autoimmune regulator Rabbit Polyclonal Antibody used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.