HSP60 Rabbit Polyclonal Antibody

About this product

HSP60, also known as chaperonins (Cpn), is a family of heat shock proteins originally sorted by their 60kDa molecular mass. They prevent misfolding of proteins during stressful situations such as high heat, by assisting protein folding. HSP60 belong to a large class of molecules that assist protein folding, called molecular chaperones. Newly made proteins usually must fold from a linear chain of amino acids into a three-dimensional tertiary structure. The energy to fold proteins is supplied by non-covalent interactions between the amino acid side chains of each protein, and by solvent effects. Most proteins spontaneously fold into their most stable three-dimensional conformation, which is usually also their functional conformation, but occasionally proteins mis-fold. Molecular chaperones catalyze protein refolding by accelerating partial unfolding of misfolded proteins, aided by energy supplied by the hydrolysis of adenosine triphosphate (ATP). Chaperonin proteins may also tag misfolded proteins to be degraded.

Specifications

Catalog number

1007-3

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

60 kDa chaperonin antibody 60 kDa heat shock protein, mitochondrial antibody CH60_HUMAN antibody Chaperonin 60 antibody Chaperonin, 60-KD antibody CPN60 antibody fa04a05 antibody GROEL antibody heat shock 60kDa protein 1 (chaperonin) antibody Heat shock protein 1 (chaperonin) antibody Heat shock protein 60 antibody Heat shock protein 65 antibody heat shock protein family D (Hsp60) member 1 antibody HLD4 antibody Hsp 60 antibody HSP 65 antibody HSP-60 antibody HSP60 antibody HSP65 antibody HSPD1 antibody HuCHA60 antibody Mitochondrial matrix protein P1 antibody P60 lymphocyte protein antibody short heat shock protein 60 Hsp60s1 antibody SPG16 antibody

Abbreviation

CPN60,HSP-60,Hsp60

Swiss Prot

P10809 Human, P63038 Mouse, P63039 Rat

Cellular Locus

Mitochondrion matrix

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human HSP60 aa 300-353.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

Hela cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, Raji cell lysate, SW480, rat kidney tissue, human kidney tissue, mouse kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:5,000-10,000 ;IF-Cell: 1:50 ;IHC-P: 1:2,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*PBS (pH7.4), 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 61 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

No