E-Cadherin Mouse Monoclonal Antibody [A0-G11-2] — image 1 of 3

Product details

E-Cadherin Mouse Monoclonal Antibody [A0-G11-2]

Catalog number EM0502

Price for EM0502

Size / count 100 µL

About this product

E-cadherin (epithelial) is the most well-studied member of the cadherin family. It consists of 5 cadherin repeats (EC1 ~ EC5) in the extracellular domain, one transmembrane domain, and an intracellular domain that binds p120-catenin and beta-catenin. The intracellular domain contains a highly-phosphorylated region vital to beta-catenin binding and, therefore, to E-cadherin function. Loss of E-cadherin function or expression has been implicated in cancer progression and metastasis. E-cadherin downregulation decreases the strength of cellular adhesion within a tissue, resulting in an increase in cellular motility. This in turn may allow cancer cells to cross the basement membrane and invade surrounding tissues. E-cadherin is also used by pathologists to diagnose different kinds of breast cancer.

Specifications

Catalog number: EM0502
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Arc 1 antibody CADH1_HUMAN antibody Cadherin 1 antibody cadherin 1 type 1 E-cadherin antibody Cadherin1 antibody CAM 120/80 antibody CD 324 antibody CD324 antibody CD324 antigen antibody cdh1 antibody CDHE antibody E-Cad/CTF3 antibody E-cadherin antibody ECAD antibody Epithelial cadherin antibody epithelial calcium dependant adhesion protein antibody LCAM antibody Liver cell adhesion molecule antibody UVO antibody Uvomorulin antibody
Abbreviation: CADH1,E-cadherin
Swiss Prot: P12830 Human, P09803 Mouse, Q9R0T4 Rat
Cellular Locus: Cell membrane.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within mouse E-Cadherin aa 350-550.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: SW480 cell lysate, A431 cell lysate,human liver carcinoma tissue, human colon carcinoma tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 97 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for E-Cadherin Mouse Monoclonal Antibody [A0-G11-2]?

The catalog number for E-Cadherin Mouse Monoclonal Antibody [A0-G11-2] is EM0502.

What sizes are available for E-Cadherin Mouse Monoclonal Antibody [A0-G11-2]?

E-Cadherin Mouse Monoclonal Antibody [A0-G11-2] is available in the following size(s): 100 µL.

Is E-Cadherin Mouse Monoclonal Antibody [A0-G11-2] in stock?

E-Cadherin Mouse Monoclonal Antibody [A0-G11-2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is E-Cadherin Mouse Monoclonal Antibody [A0-G11-2] used for?

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.