BAX Mouse Monoclonal Antibody [3-D2] — image 1 of 3

Product details

BAX Mouse Monoclonal Antibody [3-D2]

Catalog number EM1203

Price for EM1203

Size / count 100 µL

About this product

BAX is a member of the Bcl-2 gene family. Apoptosis regulator BAX promotes apoptosis by binding to and antagonizing the Bcl-2 protein. In healthy mammalian cells, the majority of BAX is found in the cytosol, but upon initiation of apoptotic signaling, Bax undergoes a conformational shift. Upon induction of apoptosis, BAX becomes organelle membrane-associated, and in particular, mitochondrial membrane associated. The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis. The p53 protein is a transcription factor that, when activated as part of the cell's response to stress, regulates many downstream target genes, including BAX.

Specifications

Catalog number: EM1203
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Apoptosis regulator BAX antibody BAX antibody Bax-protein antibody BAX_HUMAN antibody BAXA antibody Baxdelta2G9 antibody Baxdelta2G9omega antibody Baxdelta2omega antibody Bcl-2-like protein 4 antibody BCL2 associated X protein antibody BCL2 associated X protein omega antibody BCL2 associated X protein transcript variant delta2 antibody Bcl2-L-4 antibody BCL2L4 antibody membrane isoform alpha antibody
Abbreviation: Bcl2-L-4
Swiss Prot: Q07812 Human, Q07813 Mouse
Cellular Locus: Mitochondrion membrane, cytoplasm
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: This antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to N-terminal BAX.
Isotype: IgA
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Daudi cell lysate, Raji cell lysate, HepG2, Hela.
Concentration: 2 mg/mL
Dilution: WB: 1:500;IF-Cell: 1:200;IHC-P: 1:200;FC: 1:50
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 21 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for BAX Mouse Monoclonal Antibody [3-D2]?

The catalog number for BAX Mouse Monoclonal Antibody [3-D2] is EM1203.

What sizes are available for BAX Mouse Monoclonal Antibody [3-D2]?

BAX Mouse Monoclonal Antibody [3-D2] is available in the following size(s): 100 µL.

Is BAX Mouse Monoclonal Antibody [3-D2] in stock?

BAX Mouse Monoclonal Antibody [3-D2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is BAX Mouse Monoclonal Antibody [3-D2] used for?

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.