IMP3 Mouse Monoclonal Antibody [C2-E4] — image 1 of 3

Product details

IMP3 Mouse Monoclonal Antibody [C2-E4]

Catalog number EM1701-15

Price for EM1701-15

Size / count 100 µL

About this product

Insulin like growth factor 2 mRNA binding proteins (IGF2BPs) bind RNA and influence RNA synthesis and metabolism. IGF2BP1, also known as coding region determinant-binding protein/insulin-like growth factor II mRNA-binding protein (CRD-BP), IMP1 or VICKZ1; IGF2BP2 (IMP2, VICKZ2, p62); and IGF2BP2 (IMP3, KOC1, VICKZ3) contain a unique combination of RNA recognition motifs and four hnRNP K homology domains. IGF2BP1 is abundant in embryonal tissues and is expressed in 81% of colon cancers, 73% of sarcomas and 58.5% of breast cancers. It recognizes c-Myc, IGF-II and t mRNAs, and H19 RNA, and plays a major role in proliferation of K-562 cells by an IGF-II-dependent mechanism. IGF2BP2 binds the 5' UTR of IGF-II mRNA and influences tumor cell growth, in which IGF2BP2 is associated with apoptosis induced by tretinoin. IGF2BP3 knockdown by RNA interference decreases levels of IGF-II protein without affecting IGF-II, c-Myc, or β Actin mRNA and H19 RNA levels. IGF2BP3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium.

Specifications

Catalog number: EM1701-15
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Cancer/testis antigen 98 antibody CT98 antibody DKFZp686F1078 antibody hKOC antibody IF2B3_HUMAN antibody IGF II mRNA binding protein 3 antibody IGF-II mRNA-binding protein 3 antibody IGF2 mRNA binding protein 3 antibody IGF2 mRNA-binding protein 3 antibody IGF2BP3 antibody IMP 3 antibody IMP-3 antibody Insulin like growth factor 2 mRNA binding protein 3 antibody Insulin-like growth factor 2 mRNA-binding protein 3 antibody KH domain containing protein overexpressed in cancer antibody KH domain-containing protein overexpressed in cancer antibody KOC 1 antibody KOC1 antibody VICKZ 3 antibody VICKZ family member 3 antibody VICKZ3 antibody
Abbreviation: IGF2 mRNA-binding protein 3, IMP-3, hKOC, IGF2BP3, IMP3, KOC1, VICKZ3
Swiss Prot: O00425 Human, Q9CPN8 Mouse,
Cellular Locus: Cytoplasm. Nucleus.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human IMP-3 aa 352-579 / 579.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, IF-Cell, FC, IP
Positive Control: HeLa cell lysate, 293T cell lysate, mouse placenta tissue lysate, rat placenta tissue lysate, Hela, SH-SY5Y, rat brain tissue, human liver cancer tissue, human placenta tissue, mouse testis tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:50 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: 1-2μg/sample
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 64 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for IMP3 Mouse Monoclonal Antibody [C2-E4]?

The catalog number for IMP3 Mouse Monoclonal Antibody [C2-E4] is EM1701-15.

What sizes are available for IMP3 Mouse Monoclonal Antibody [C2-E4]?

IMP3 Mouse Monoclonal Antibody [C2-E4] is available in the following size(s): 100 µL.

Is IMP3 Mouse Monoclonal Antibody [C2-E4] in stock?

IMP3 Mouse Monoclonal Antibody [C2-E4] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IMP3 Mouse Monoclonal Antibody [C2-E4] used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.