Tim3 Mouse Monoclonal Antibody [1E5] — image 1 of 3

Product details

Tim3 Mouse Monoclonal Antibody [1E5]

Catalog number EM1701-20

Price for EM1701-20

Size / count 100 µL

About this product

Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. In CD8+ cells attenuates TCR-induced signaling, specifically by blocking NF-kappaB and NFAT promoter activities resulting in the loss of IL-2 secretion. The function may implicate its association with LCK proposed to impair phosphorylation of TCR subunits, and/or LGALS9-dependent recruitment of PTPRC to the immunological synapse.

Specifications

Catalog number: EM1701-20
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CD366 antibody FLJ14428 antibody HAVcr-2 antibody Havcr2 antibody HAVR2_HUMAN antibody Hepatitis A virus cellular receptor 2 antibody Kidney injury molecule 3 antibody KIM 3 antibody KIM3 antibody T cell immunoglobulin and mucin domain containing 3 antibody T cell immunoglobulin mucin 3 antibody T-cell immunoglobulin and mucin domain-containing protein 3 antibody T-cell immunoglobulin mucin family member 3 antibody T-cell immunoglobulin mucin receptor 3 antibody T-cell membrane protein 3 antibody Tim 3 antibody TIM-3 antibody TIM3 antibody TIMD-3 antibody TIMD3 antibody
Abbreviation: HAVcr-2, TIMD-3, TIM-3, HAVCR2, TIM3, TIMD3
Swiss Prot: Q8TDQ0 Human
Cellular Locus: Membrane. Cell junction.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein with Human Tim3 1-89 / 301.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: THP-1 cell lysate, A549 cell lysate, HepG2 cell lysate, human lung cancer tissue, human spleen tissue, human tonsil tissue, 293T, Daudi.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:100-1:200 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 33 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Tim3 Mouse Monoclonal Antibody [1E5]?

The catalog number for Tim3 Mouse Monoclonal Antibody [1E5] is EM1701-20.

What sizes are available for Tim3 Mouse Monoclonal Antibody [1E5]?

Tim3 Mouse Monoclonal Antibody [1E5] is available in the following size(s): 100 µL.

Is Tim3 Mouse Monoclonal Antibody [1E5] in stock?

Tim3 Mouse Monoclonal Antibody [1E5] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tim3 Mouse Monoclonal Antibody [1E5] used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.