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Product details

AKR1C1 Mouse Monoclonal Antibody [5-F10]

Catalog number EM1701-21

Price for EM1701-21

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Size / count 100 µL

About this product

Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids. Most probably acts as a reductase in vivo since the oxidase activity measured in vitro is inhibited by physiological concentrations of NADPH. Displays a broad positional specificity acting on positions 3, 17 and 20 of steroids and regulates the metabolism of hormones like estrogens and androgens. May also reduce conjugated steroids such as 5alpha-dihydrotestosterone sulfate. Displays affinity for bile acids.

Specifications

Catalog number
EM1701-21
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
2-dihydrobenzene-1 antibody 2-diol dehydrogenase antibody 20 alpha (3 alpha) hydroxysteroid dehydrogenase antibody 20 ALPHA HSD antibody 20 alpha hydroxysteroid dehydrogenase antibody 20-alpha-HSD antibody 20-alpha-hydroxysteroid dehydrogenase antibody 20ALPHAHSD antibody 2ALPHAHSD antibody AK1C1 antibody AK1C1_HUMAN antibody AKR1C1 antibody Aldo keto reductase family 1 member C1 antibody aldo-keto reductase C antibody Aldo-keto reductase family 1 member C1 antibody Aldo-keto reductase family, 1 member 1 antibody C9 antibody Chlordecone reductase homolog antibody Chlordecone reductase homolog HAKRC antibody DD1 antibody DD1/DD2 antibody DDH antibody DDH1 antibody Dihydrodiol dehydrogenase 1 antibody Dihydrodiol dehydrogenase 1/2 antibody dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase antibody dihydrodiol dehydrogenase isoform DD1 antibody Dihydrodiol dehydrogenase, type 1 antibody H37 antibody HAKRC antibody HBAB antibody Hepatic dihydrodiol dehydrogenase antibody High affinity hepatic bile acid-binding protein antibody High-affinity hepatic bile acid-binding protein antibody Indanol dehydrogenase antibody MBAB antibody MGC8954 antibody Trans-1 antibody Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase antibody Type II 3 alpha hydroxysteroid dehydrogenase antibody
Abbreviation
20-alpha-HSD, DD1/DD2, HBAB, AKR1C1, DDH, DDH1
Swiss Prot
Q04828 Human
Cellular Locus
Cytoplasm.
Host
Mouse
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within Human AKR1C1 aa 180-323 / 323.
Isotype
IgG2a
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HepG2 cell lysate, U-87 MG cell lysate, HeLa cell lysate, A431 cell lysate, human liver tissue lysate, human liver tissue, human pancreas tissue, mouse kidney tissue.
Concentration
2 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for AKR1C1 Mouse Monoclonal Antibody [5-F10]?

The catalog number for AKR1C1 Mouse Monoclonal Antibody [5-F10] is EM1701-21.

What sizes are available for AKR1C1 Mouse Monoclonal Antibody [5-F10]?

AKR1C1 Mouse Monoclonal Antibody [5-F10] is available in the following size(s): 100 µL.

Is AKR1C1 Mouse Monoclonal Antibody [5-F10] in stock?

AKR1C1 Mouse Monoclonal Antibody [5-F10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is AKR1C1 Mouse Monoclonal Antibody [5-F10] used for?

Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids. Most probably acts as a reductase in vivo since the oxidase activity measured in vitro is inhibited by physiological concentrations of NADPH. Displays a broad positional specificit

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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