PCSK9 Mouse Monoclonal Antibody [2F1] — image 1 of 3

Product details

PCSK9 Mouse Monoclonal Antibody [2F1]

Catalog number EM1701-26

Price for EM1701-26

Size / count 100 µL

About this product

Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC-1, is a 692 amino acid protein that belongs to the peptidase S8 family and contains one peptidase S8 domain. Important in the regulation of plasma cholesterol homeostasis, PCSK9 binds to low-density lipid receptor family members LDLR, very low-density lipid receptor (VLDLR) and apolipoprotein receptor 2 (ApoER2) and promotes their degradation in intracellular acidic compartments. PCSK9 also plays a role in neuronal differentiation and apoptosis. PCSK9 is expressed in Shwann cells, neuro-epithelioma, colon carcinoma, and hepatic and pancreatic cell lines. PCSK9 levels in the brain are highest in the cerebellum during perinatal development, with ischemia causing increased levels in the adult brain. Defects in the gene encoding this protein causes the autosomal dominant disorder familial hypercholesterolemia 3 (HCHOLA3).

Specifications

Catalog number: EM1701-26
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Convertase subtilisin/kexin type 9 preproprotein antibody FH3 antibody HCHOLA3 antibody Hypercholesterolemia autosomal dominant 3 antibody LDLCQ1 antibody NARC 1 antibody NARC-1 antibody NARC1 antibody Neural apoptosis regulated convertase 1 antibody Neural apoptosis-regulated convertase 1 antibody PC 9 antibody PC9 antibody PCSK 9 antibody PCSK9 antibody PCSK9_HUMAN antibody Proprotein convertase 9 antibody Proprotein convertase PC9 antibody Proprotein convertase subtilisin/kexin type 9 antibody PSEC0052 antibody Subtilisin/kexin like protease PC9 antibody Subtilisin/kexin-like protease PC9 antibody
Abbreviation: NARC-1, PC9, PCSK9, NARC1, PSEC0052
Swiss Prot: Q8NBP7 Human, Q80W65 Mouse
Cellular Locus: Secreted, endoplasmic reticulum,lysosome, cytoplasm.
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein with Human PCSK9 1-201 / 692.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, IF-Cell, FC
Positive Control: PANC-1, H22, SW1990, HepG2, human liver tissue, human colon cancer tissue, human kidney tissue, mouse kidney tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 74 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PCSK9 Mouse Monoclonal Antibody [2F1]?

The catalog number for PCSK9 Mouse Monoclonal Antibody [2F1] is EM1701-26.

What sizes are available for PCSK9 Mouse Monoclonal Antibody [2F1]?

PCSK9 Mouse Monoclonal Antibody [2F1] is available in the following size(s): 100 µL.

Is PCSK9 Mouse Monoclonal Antibody [2F1] in stock?

PCSK9 Mouse Monoclonal Antibody [2F1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PCSK9 Mouse Monoclonal Antibody [2F1] used for?

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.