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Product details

Insulin Mouse Monoclonal Antibody [5E1]

Catalog number EM1701-33

Price for EM1701-33

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Size / count 100 µL

About this product

Insulin is a secreted peptide hormone that elicits metabolic effects such as increases in glucose uptake and glycogen synthesis leading to a decrease in blood glucose concentration. Insulin is first formed as a precursor molecule, preproinsulin, which is later cleaved to proinsulin and finally to the mature insulin hormone. Mature insulin consists of 51 amino acids, contained within an A chain and a B chain that are connected by two disulfide bridges. It increases cell permeability to monosaccharides, amino acids and fatty acids. Insulin is secreted by the pancreas at basal levels in the absence of exogenous stimuli, with secretion increasing in response to glucose. Insulin action is effected by the binding of insulin to cell-surface receptors on the target cell membrane. Defects of insulin are the cause of hyperproinsulinemia and of type-II diabetes mellitus.

Specifications

Catalog number
EM1701-33
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
IDDM antibody IDDM1 antibody IDDM2 antibody ILPR antibody ins antibody INS_HUMAN antibody Insulin A chain antibody Insulin B chain antibody IRDN antibody MODY10 antibody Preproinsulin antibody Proinsulin antibody Proinsulin precursor antibody
Abbreviation
INS
Swiss Prot
P01308 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human Insulin aa 1-130.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
IHC-P, ELISA
Positive Control
Human pancreas tissue.
Concentration
2 mg/mL
Dilution
IHC-P: 1:2,000-1:10,000 ;ELISA: 1:5,000-1:20,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 12 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Insulin Mouse Monoclonal Antibody [5E1]?

The catalog number for Insulin Mouse Monoclonal Antibody [5E1] is EM1701-33.

What sizes are available for Insulin Mouse Monoclonal Antibody [5E1]?

Insulin Mouse Monoclonal Antibody [5E1] is available in the following size(s): 100 µL.

Is Insulin Mouse Monoclonal Antibody [5E1] in stock?

Insulin Mouse Monoclonal Antibody [5E1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Insulin Mouse Monoclonal Antibody [5E1] used for?

Insulin is a secreted peptide hormone that elicits metabolic effects such as increases in glucose uptake and glycogen synthesis leading to a decrease in blood glucose concentration. Insulin is first formed as a precursor molecule, preproinsulin, which is later cleaved to proinsulin and finally to th

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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