CD11b Mouse Monoclonal Antibody [4-6] — image 1 of 3

Product details

CD11b Mouse Monoclonal Antibody [4-6]

Catalog number EM1701-42

Price for EM1701-42

Size / count 100 µL

About this product

Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils. May play a role in mast cell development.

Specifications

Catalog number: EM1701-42
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: antigen CD11b (p170) antibody Antigen CD11b p170 antibody CD11 antigen like family member B antibody CD11 antigen-like family member B antibody CD11b antibody CD11b/CD18 antibody CD49d antibody Cell surface glycoprotein MAC-1 subunit alpha antibody Complement component 3 receptor 3 subunit antibody Complement Component Receptor 3 Alpha antibody Complement receptor type 3, alpha subunit antibody CR 3 alpha chain (CR3A) antibody CR 3 alpha chain antibody CR-3 alpha chain antibody CR3 antibody CR3A antibody F730045J24Rik antibody Integrin Alpha M antibody Integrin alpha M chain antibody Integrin alpha-M antibody Integrin beta 2 alpha subunit antibody Integrin subunit alpha M antibody integrin, alpha M (complement component 3 receptor 3 subunit) antibody ITAM_HUMAN antibody ITGAM antibody Leukocyte adhesion receptor MO1 antibody Ly-40 antibody MAC 1 antibody Mac-1a antibody MAC1 antibody Mac1, alpha subunit antibody MAC1A antibody Macrophage antigen alpha polypeptide antibody MGC117044 antibody Mo1, alpha subunit antibody MO1A antibody Neutrophil adherence receptor alpha M subunit antibody Neutrophil adherence receptor antibody SLEB6 antibody
Abbreviation: ITGAM, CD11B, CR3A
Swiss Prot: P11215 Human
Cellular Locus: Cell membrane.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within Human CD11b aa 544-743 / 1,152.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: IHC-P, IF-Cell, FC, WB
Positive Control: TF-1 cell lysate, THP-1 cell lysate, U-937 cell lysate, A431, LOVO, human tonsil tissue, human spleen tissue.
Concentration: 2 mg/mL
Dilution: IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC:1:50-1:100 ;WB: 1:1,000
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 127 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD11b Mouse Monoclonal Antibody [4-6]?

The catalog number for CD11b Mouse Monoclonal Antibody [4-6] is EM1701-42.

What sizes are available for CD11b Mouse Monoclonal Antibody [4-6]?

CD11b Mouse Monoclonal Antibody [4-6] is available in the following size(s): 100 µL.

Is CD11b Mouse Monoclonal Antibody [4-6] in stock?

CD11b Mouse Monoclonal Antibody [4-6] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD11b Mouse Monoclonal Antibody [4-6] used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.