IL-6 Mouse Monoclonal Antibody [1-6] — image 1 of 3

Product details

IL-6 Mouse Monoclonal Antibody [1-6]

Catalog number EM1701-45

Price for EM1701-45

Size / count 100 µL

About this product

Interleukin-6, or IL-6, is a multifunctional protein, 212 amino acids in length, that plays critical roles in host defense, immune response and hematopoiesis. IL-6 is constitutively expressed by epidermal Langerhans cells and its expression is induced in stimulated keratinocytes. IL-6, IL-1β and TNFα act as endogenous pyrogens, regulating the fever response to bacterial invasion. The IL-6 receptor is a trimeric complex composed of an IL-6-specific α chain and a homodimer of the gp130 glycoprotein common to the IL-6, IL-11, CNTF, OSM and LIF receptors. Stimulation with IL-6 leads to gp130 homodimerization and the activation of associated kinases JAK1 and JAK2. Once activated, JAK1 and JAK2 phosphorylate Stat3, causing its nuclear translocation and transcription of Stat3-responsive genes. IL-6 has also been shown to activate the Ras/MAP kinase pathway, which regulates NFIL6 transcription.

Specifications

Catalog number: EM1701-45
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Interleukin BSF 2 antibody B cell differentiation factor antibody B cell stimulatory factor 2 antibody B-cell stimulatory factor 2 antibody BSF 2 antibody BSF-2 antibody BSF2 antibody CDF antibody CTL differentiation factor antibody Hepatocyte stimulatory factor antibody HGF antibody HSF antibody Hybridoma growth factor antibody Hybridoma growth factor Interferon beta-2 antibody IFN-beta-2 antibody IFNB2 antibody IL 6 antibody IL-6 antibody IL6 antibody IL6_HUMAN antibody Interferon beta 2 antibody Interferon beta-2 antibody Interleukin 6 antibody Interleukin 6 (interferon beta 2) antibody Interleukin BSF 2 antibody Interleukin-6 antibody
Abbreviation: IL-6, BSF-2, CDF, IFN-beta-2, IL6, IFNB2
Swiss Prot: P08505 Mouse
Cellular Locus: Secreted.
Host: Mouse
Species Reactivity: Mouse, Rat
Immunogen: Recombinant protein within Mouse IL-6 aa 1-211 / 211.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell
Positive Control: Recombinant protein lysates, NIH/3T3.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:1,000
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 24 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for IL-6 Mouse Monoclonal Antibody [1-6]?

The catalog number for IL-6 Mouse Monoclonal Antibody [1-6] is EM1701-45.

What sizes are available for IL-6 Mouse Monoclonal Antibody [1-6]?

IL-6 Mouse Monoclonal Antibody [1-6] is available in the following size(s): 100 µL.

Is IL-6 Mouse Monoclonal Antibody [1-6] in stock?

IL-6 Mouse Monoclonal Antibody [1-6] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IL-6 Mouse Monoclonal Antibody [1-6] used for?

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.